Yazar "Açılan, Ceyda" için listeleme
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Biochemical and proteomic analysis of a potential anticancer agent: Palladium(II) saccharinate complex of terpyridine acting through double strand break formation
Adıgüzel, Zelal; Baykal, Ahmet Tarık; Kaçar, Ömer; Yılmaz, Veysel Turan; Ulukaya, Engin; Açılan, Ceyda (American Chemical Society, 2014)Metal based chemotherapeutic drugs are widely used as an effective method to defeat various cancers. In this study, the mechanism of action of a novel therapeutic agent, [Pd(sac)(terpy)](sac)center dot 4H(2)O (sac = ... -
Evaluation of apoptotic molecular pathways for smooth muscle cells isolated from thoracic aortic aneurysms in response to oxidized sterols
Adıgüzel, Zelal; Arda, Nazlı; Kaçar, Ömer; Serhatlı, Müge; Gezer Taş, Serpil; Baykal, Ahmet Tarık; Baysal, Kemal; Açılan, Ceyda (Springer, 2014)Oxysterols, oxygenated derivatives of cholesterol, are found abundantly in the plasma and atherosclerotic plaques, a common risk factor for thoracic aortic aneurysms (TAAs). Among the oxysterols, namely 7-ketocholesterol ... -
Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendritic cell generation
Hatipoğlu, İbrahim; Ercan, Duygu; Açılan, Ceyda; Başalp, Aynur; Durali, Deniz; Baykal, Ahmet Tarık (Elsevier, 2014)Hepatitis B virus (HBV) continues to be a serious worldwide health problem despite the use of protective HBV vaccines and therapeutic regimens against chronic HBV infection. Chronic HBV patients cannot induce sufficient ... -
Proteomic study of the microdissected aortic media in human thoracic aortic aneurysms
Serhatlı, Müge; Baysal, Kemal; Açılan, Ceyda; Tuncer, Eylem; Bekpınar, Seldağ; Baykal, Ahmet Tarık (American Chemical Society, 2014)Aortic aneurysm is a complex multifactorial disease, and its molecular mechanism is not understood. In thoracic aortic aneurysm (TAA), the expansion of the aortic wall is lead by extracellular matrix (ECM) degeneration in ...